The Big Bang Theory, created by Chuck Lorre and Bill Prady, premiered on September 24, 2007, on CBS. The first season introduces us to a group of socially awkward scientists and their neighbor, a waitress and aspiring actress, as they navigate life, love, and science. This season sets the tone for the show's successful run, establishing the core characters, their relationships, and the show's unique blend of humor, geek culture, and heart.